“Human Reproduction” MCQ with Answer Explanation : NEET 2025.

Here below we cover basic human reproduction MCQ (multiple choice question) question with answer for any compitative exam. Lets check one by one.

1. Which of the following hormone is responsible for ovulation?
   a) FSH
   b) LH
   c) Estrogen
   d) Progesterone

Answer: b) LH

Explanation:
The luteinizing hormone (LH) surge triggers ovulation. It causes the rupture of the Graafian follicle, releasing the ovum. Follicle-stimulating hormone (FSH) helps in follicle growth, while estrogen and progesterone regulate different stages of the menstrual cycle.

2. Which of the following cells in the testes secrete testosterone?
   a) Sertoli cells
   b) Leydig cells
   c) Spermatogonia
   d) Spermatocytes

Answer: b) Leydig cells

Explanation:
Leydig cells, also known as interstitial cells, are responsible for producing testosterone in the presence of luteinizing hormone (LH). Sertoli cells provide nourishment to sperm cells.

3. What is the site of fertilization in humans?
   a) Vagina
   b) Uterus
   c) Fallopian tube
   d) Ovary

Answer: c) Fallopian tube

Explanation:
Fertilization in humans typically occurs in the ampulla, a part of the fallopian tube. After the sperm meets the egg here, the fertilized egg (zygote) travels to the uterus for implantation.

4. Which layer of the uterus is shed during menstruation?
   a) Myometrium
   b) Endometrium
   c) Perimetrium
   d) Exometrium

Answer: b) Endometrium

Explanation:
The endometrium is the innermost lining of the uterus that thickens during the menstrual cycle in preparation for potential pregnancy. If fertilization does not occur, this layer is shed during menstruation.

5. The process of sperm maturation occurs in the:
   a) Seminiferous tubules
   b) Vas deferens
   c) Epididymis
   d) Urethra

Answer: c) Epididymis

Explanation:
Sperm are produced in the seminiferous tubules but undergo maturation and gain motility in the epididymis. This process ensures that the sperm are capable of fertilizing an ovum.

6. What is the name of the hormone responsible for the maintenance of pregnancy?
   a) Estrogen
   b) Progesterone
   c) Oxytocin
   d) Prolactin

Answer: b) Progesterone

Explanation:
Progesterone is crucial for maintaining the endometrial lining of the uterus, which is essential for a successful pregnancy. It prevents uterine contractions and supports the embryo’s development.

7. Which of the following prevents polyspermy during fertilization?
   a) Zona pellucida reaction
   b) Acrosome reaction
   c) Cortical reaction
   d) Capacitation

Answer: c) Cortical reaction

Explanation:
The cortical reaction occurs after a sperm enters the egg, releasing enzymes from cortical granules that modify the zona pellucida to prevent further sperm from entering, thus avoiding polyspermy.

8. The fetal part of the placenta is derived from:
   a) Endometrium
   b) Chorion
   c) Amnion
   d) Allantois

Answer: b) Chorion

Explanation:
The fetal part of the placenta is derived from the chorion, which develops from the trophoblast cells. The placenta plays a vital role in nutrient exchange between the mother and the fetus.

9. At what stage is the oocyte arrested in a newborn female?
   a) Primary oocyte in prophase I
   b) Secondary oocyte in metaphase II
   c) Oogonia
   d) Zygote

Answer: a) Primary oocyte in prophase I

Explanation:
In a newborn female, oocytes are arrested in the diplotene stage of prophase I of meiosis. They remain in this stage until puberty, when they resume meiotic division during ovulation.

10. Which of the following is the correct sequence of sperm formation?
    a) Spermatogonia → Spermatocyte → Spermatid → Sperm
    b) Spermatocyte → Spermatogonia → Spermatid → Sperm
    c) Spermatid → Spermatogonia → Spermatocyte → Sperm
    d) Sperm → Spermatid → Spermatogonia → Spermatocyte

Answer: a) Spermatogonia → Spermatocyte → Spermatid → Sperm

Explanation:
Spermatogenesis begins with spermatogonia (stem cells), which differentiate into primary spermatocytes. These then undergo meiosis to form spermatids, which finally mature into spermatozoa (sperm).